Tissue Plasminogen Activators(Tenecteplase) is in a group of drugs called tissue plasminogen activators (TPAs). It works by causing the body to over-produce a substance called plasmin to dissolve unwanted blood clots. Tenecteplase is used to prevent death from a heart attack (acute myocardial infarction). Tenecteplase may also be used for other purposes not listed in this medication guide.

Tell your caregivers at once if you have a serious side effect such as:

• Blood in your urine or stools
• Nosebleed, coughing up blood
• Bleeding from a recent injury or surgery incision
• Bleeding around the IV needle
• Fast, slow, or uneven heart rate
• Feeling like you might pass out